The Department of Laboratory Medicine & Pathology at the University of Washington in Seattle has two (2) outstanding openings for a Research Scientist/Engineer 3 (full-time, day shift) in the Dr. Alex Greninger Lab. This position supports viral genomics and determinants of viral growth.
WHAT WE OFFER:
- Vacation time and sick time off that accrues monthly, including 12 paid holidays.
- Fully subsidized public transit pass (U-PASS) that covers multiple forms of public transportation in the region.
- Excellent healthcare, dental, disability, and retirement plan options.
- State Employee Tuition Exemption Program covering up to 6 credits of qualifying coursework per quarter at the UW or other participating colleges or universities.
- Eligibility for the Public Service Loan Forgiveness Program as a UW employee.
- Free fitness, healthy eating, finance, and stress reduction classes offered through the Whole U.
- And much more! Please click HERE for a comprehensive benefits summary.
WHAT YOU’LL DO:
Experiment/Research/Project Management (80%)
- Creation and optimization of metagenomic next-generation sequencing libraries for unbiased pathogen detection and viral genome recovery. Genome finishing of novel viruses, including optimization of high-throughput methods.
- Development of next-generation sequencing analysis pipelines for taxonomical analysis and viral genome visualization.
- Development of phage display serological profiling tools to investigate high-resolution interrogation of serological response, including creation of analysis tools.
- Perform high-level viral culture in novel culture models and reverse genetics work, analyze data compile results and draft reports for incoming research awards and contracts.
- Supervise and analyze quantitative viral load determination using RT-qPCR, qPCR, ddPCR, including optimization of new assays.
- Supervise performance of molecular procedures including but not limited to real-time PCR, Sanger sequencing, PCR product detection DNA sequencing and next generation sequencing.
- Perform work accurately, precisely and meet test completion deadlines.
- Maintain complete, accurate, legible, secure records. Thoroughly document any modifications using appropriate document and version control.
- Analyze experimental data and report to the Director and Lab Supervisor; determine what modifications and follow-up experiments are necessary to generate relevant data.
- Identify long and short term goals; initiate research program/projects.
- Contribute technical knowledge when initiating new projects to determining feasibility of goals and objectives of the study.
- Contribute data and analyses for grant submissions.
- Perform preliminary experiments for assay development.
- Work with R, python, Geneious, Excel, and bash command line.
- Accommodate schedule changes to cooperatively accomplish required daily work, coordinate with Laboratory supervisor/manager.
- Collaborate with research team to create opportunities and ancillary research projects to enhance technical assay methodology or content through the expansion of existing or development of new projects.
- Review the scientific process of each research project, analyze issues, understand scientific procedures and statistical analysis; report data using graphs and charts.
- Prepare manuscripts for publication.
- Provide ongoing feedback; identify development opportunities and actively solicit input on work methods.
Other Duties (20%)
- Provide ongoing feedback; identify development opportunities and actively solicit input on work methods.
- Train and monitor new employees and guest technicians in experimental procedures and assays, laboratory safety and database maintenance.
- Perform other duties as required.
WHAT YOU’LL NEED:
Bachelor’s degree in molecular biology, virology, or genomics AND 4 years of relevant experience, OR Equivalent combination of education/experience.
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
DESIRED QUALIFICATIONS:
- Prior mammalian cell culture experience
- Prior coding experience
- Previous experience with next-generation sequencing analysis and genomics
- Strong written and communication skills
- Ability to problem-solve and troubleshoot
- Proficient at R, python, and/or bash.
- Experience with other herpesvirus reverse genetics systems
- Data analysis skills with basic statistical knowledge
About us:
A regional resource for clinical laboratory services required for innovative patient care, research and educational programs, the Department of Laboratory Medicine & Pathology at the UW combines the sophisticated testing and informatics capabilities of fully accredited laboratories with the resources of an academic institution in its delivery of clinical and anatomic pathology services. Recognized for excellence in clinical training, world-class research initiatives, and a commitment to community service, we serve labs and medical facilities both nationally and internationally.
To learn more about our team, please click HERE.
Additional information:
UW Medicine includes Harborview Medical Center, UW Medical Center – Montlake, UW Medical Center – Northwest, Valley Medical Center, UW Neighborhood Clinics, UW Physicians, UW School of Medicine, and Airlift Northwest.
Committed to attracting and retaining a diverse staff, the University of Washington will honor your experiences, perspectives and unique identity. Together, our community strives to create and maintain working and learning environments that are inclusive, equitable and welcoming.
The University of Washington is an affirmative action and equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
To request disability accommodation in the application process, contact the Disability Services Office at 206-543-6450 or dso@uw.edu.
Applicants considered for this position will be required to disclose if they are the subject of any substantiated findings or current investigations related to sexual misconduct at their current employment and past employment. Disclosure is required under Washington state law.